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Phospho YAP (S127) Cell-Based Colorimetric ELISA Kit

商品貨號(hào)： PLA000394

適應(yīng) 性： 人,小鼠,大鼠

￥2400元

規(guī)格：

96T

在線咨詢

MSDS

說(shuō)明書

商品描述

發(fā)貨日期： 14
基因名稱： YAP1
Human_gene_id： 10413
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10413
Human_swiss_prot_no： P46937
Human_swiss_link： http://www.uniprot.org/uniprotkb/P46937/entry
Mouse_swiss_prot_no： P46938
Mouse_swiss_link： http://www.uniprot.org/uniprot/P46938
Rat_swiss_prot_no： Q2EJA0
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q2EJA0
儲(chǔ)存： 2-8°C/6 months
說(shuō)明書： KA1392C.pdf
其他名稱： Yorkie homolog (65 kDa Yes-associated protein) (YAP65)
功能： regulation of transcription, DNA-dependent,?regulation of transcription from RNA polymerase II promoter,?positive regulation of biosynthetic process,?positive regulation of macromolecule biosynthetic process,?positive regulation of macromolecule metabolic process,?positive regulation of gene expression,?positive regulation of cellular biosynthetic process,?regulation of transcription,?positive regulation of transcription, DNA-dependent,?positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,?positive regulation of transcription,?positive regulation of transcription from RNA polymerase II promoter,?positive regulation of nitrogen compound metabolic process,?regulation of RNA metabolic process,?positive regulation of RNA metabolic process,
相關(guān)產(chǎn)品： YT4924,YT4923,YP0708,KA3612C,KA1392C
細(xì)胞定位： Cytoplasm . Nucleus . Both phosphorylation and cell density can regulate its subcellular localization (PubMed:18158288, PubMed:20048001). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (PubMed:18158288, PubMed:20048001). At low density, predominantly nuclear and is translocated to the cytoplasm at high density (PubMed:18158288, PubMed:20048001, PubMed:25849865). PTPN14 induces translocation from the nucleus to the cytoplasm (PubMed:22525271). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .
組織表達(dá)： Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level).
科研貨號(hào)： PLA000394

Phospho YAP (S127) Cell-Based Colorimetric ELISA Kit

Catalog No PLA000394

Product information

發(fā)貨日期： 14
基因名稱： YAP1
Human_gene_id： 10413
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10413
Human_swiss_prot_no： P46937
Human_swiss_link： http://www.uniprot.org/uniprotkb/P46937/entry
Mouse_swiss_prot_no： P46938
Mouse_swiss_link： http://www.uniprot.org/uniprot/P46938
Rat_swiss_prot_no： Q2EJA0
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q2EJA0
儲(chǔ)存： 2-8°C/6 months
說(shuō)明書： KA1392C.pdf
其他名稱： Yorkie homolog (65 kDa Yes-associated protein) (YAP65)
功能： regulation of transcription, DNA-dependent,?regulation of transcription from RNA polymerase II promoter,?positive regulation of biosynthetic process,?positive regulation of macromolecule biosynthetic process,?positive regulation of macromolecule metabolic process,?positive regulation of gene expression,?positive regulation of cellular biosynthetic process,?regulation of transcription,?positive regulation of transcription, DNA-dependent,?positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,?positive regulation of transcription,?positive regulation of transcription from RNA polymerase II promoter,?positive regulation of nitrogen compound metabolic process,?regulation of RNA metabolic process,?positive regulation of RNA metabolic process,
相關(guān)產(chǎn)品： YT4924,YT4923,YP0708,KA3612C,KA1392C
細(xì)胞定位： Cytoplasm . Nucleus . Both phosphorylation and cell density can regulate its subcellular localization (PubMed:18158288, PubMed:20048001). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (PubMed:18158288, PubMed:20048001). At low density, predominantly nuclear and is translocated to the cytoplasm at high density (PubMed:18158288, PubMed:20048001, PubMed:25849865). PTPN14 induces translocation from the nucleus to the cytoplasm (PubMed:22525271). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .
組織表達(dá)： Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level).
科研貨號(hào)： PLA000394

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