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Phospho ACK1 (Y284) Cell-Based Colorimetric ELISA Kit

商品貨號： PLA000354

適應(yīng) 性： 人,小鼠

￥2400元

規(guī)格：

96T

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MSDS

說明書

商品描述

發(fā)貨日期： 14
基因名稱： TNK2
Human_gene_id： 10188
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10188
Human_swiss_prot_no： Q07912
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q07912/entry
Mouse_swiss_prot_no： O54967
Mouse_swiss_link： http://www.uniprot.org/uniprot/O54967
儲存： 2-8°C/6 months
說明書： KA1352C.pdf
其他名稱： Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
功能： regulation of protein amino acid phosphorylation,?positive regulation of protein amino acid phosphorylation,?protein amino acid phosphorylation,?phosphorus metabolic process,?phosphate metabolic process,?intracellular signaling cascade,?small GTPase mediated signal transduction,?positive regulation of phosphorus metabolic process,?positive regulation of macromolecule metabolic process,?phosphorylation,?regulation of phosphate metabolic process,regulation of protein modification process,?positive regulation of protein modification process,?regulation of cellular protein metabolic process,?positive regulation of cellular protein metabolic process,?regulation of phosphorylation,positive regulation of phosphorylation,?positive regulation of phosphate metabolic process,?regulation of peptidyl-tyrosine phosphorylation,?positive regulation of peptidyl-tyrosine phosphorylation,?regulation of phosphorus metabolic process,?positive regulation of protein metabolic process,
相關(guān)產(chǎn)品： YT5018,YP0897,KA3986C,KA1352C
細(xì)胞定位： Cell membrane . Nucleus . Endosome . Cell junction, adherens junction . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle, clathrin-coated vesicle . Membrane, clathrin-coated pit . Cytoplasm, perinuclear region . Cytoplasm, cytosol . The Tyr-284 phosphorylated form is found both in the membrane and nucleus (By similarity). Co-localizes with EGFR on endosomes (PubMed:20333297). Nuclear translocation is CDC42-dependent (By similarity). Detected in long filamentous cytosolic structures where it co-localizes with CTPS1 (By similarity). .
組織表達(dá)： The Tyr-284 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. It also shows a significant increase in expression in prostate cancers during the progressive stages.
科研貨號： PLA000354

Phospho ACK1 (Y284) Cell-Based Colorimetric ELISA Kit

Catalog No PLA000354

Product information

發(fā)貨日期： 14
基因名稱： TNK2
Human_gene_id： 10188
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10188
Human_swiss_prot_no： Q07912
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q07912/entry
Mouse_swiss_prot_no： O54967
Mouse_swiss_link： http://www.uniprot.org/uniprot/O54967
儲存： 2-8°C/6 months
說明書： KA1352C.pdf
其他名稱： Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
功能： regulation of protein amino acid phosphorylation,?positive regulation of protein amino acid phosphorylation,?protein amino acid phosphorylation,?phosphorus metabolic process,?phosphate metabolic process,?intracellular signaling cascade,?small GTPase mediated signal transduction,?positive regulation of phosphorus metabolic process,?positive regulation of macromolecule metabolic process,?phosphorylation,?regulation of phosphate metabolic process,regulation of protein modification process,?positive regulation of protein modification process,?regulation of cellular protein metabolic process,?positive regulation of cellular protein metabolic process,?regulation of phosphorylation,positive regulation of phosphorylation,?positive regulation of phosphate metabolic process,?regulation of peptidyl-tyrosine phosphorylation,?positive regulation of peptidyl-tyrosine phosphorylation,?regulation of phosphorus metabolic process,?positive regulation of protein metabolic process,
相關(guān)產(chǎn)品： YT5018,YP0897,KA3986C,KA1352C
細(xì)胞定位： Cell membrane . Nucleus . Endosome . Cell junction, adherens junction . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle, clathrin-coated vesicle . Membrane, clathrin-coated pit . Cytoplasm, perinuclear region . Cytoplasm, cytosol . The Tyr-284 phosphorylated form is found both in the membrane and nucleus (By similarity). Co-localizes with EGFR on endosomes (PubMed:20333297). Nuclear translocation is CDC42-dependent (By similarity). Detected in long filamentous cytosolic structures where it co-localizes with CTPS1 (By similarity). .
組織表達(dá)： The Tyr-284 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. It also shows a significant increase in expression in prostate cancers during the progressive stages.
科研貨號： PLA000354

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